Therapeutic activity of an interleukin-4/interleukin-13 dual antagonist on oxazolone-induced colitis in mice

Interleukin-4 (IL-4) and IL-13 are critical drivers of immune activation and inflammation in ulcerative colitis, asthma and other diseases. Because these cytokines may have redundant function, dual targeting holds promise for achieving greater efficacy. We have recently described a bifunctional ther...

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Autors principals: Kasaian, Marion T, Page, Karen M, Fish, Susan, Brennan, Agnes, Cook, Timothy A, Moreira, Karen, Zhang, Melvin, Jesson, Michael, Marquette, Kimberly, Agostinelli, Rita, Lee, Julie, Williams, Cara M M, Tchistiakova, Lioudmila, Thakker, Paresh
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2014
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4212955/
https://ncbi.nlm.nih.gov/pubmed/24831554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12319
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