Therapeutic activity of an interleukin-4/interleukin-13 dual antagonist on oxazolone-induced colitis in mice

Interleukin-4 (IL-4) and IL-13 are critical drivers of immune activation and inflammation in ulcerative colitis, asthma and other diseases. Because these cytokines may have redundant function, dual targeting holds promise for achieving greater efficacy. We have recently described a bifunctional ther...

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Detaylı Bibliyografya
Asıl Yazarlar: Kasaian, Marion T, Page, Karen M, Fish, Susan, Brennan, Agnes, Cook, Timothy A, Moreira, Karen, Zhang, Melvin, Jesson, Michael, Marquette, Kimberly, Agostinelli, Rita, Lee, Julie, Williams, Cara M M, Tchistiakova, Lioudmila, Thakker, Paresh
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Blackwell Science Inc 2014
Konular:
Original Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4212955/
https://ncbi.nlm.nih.gov/pubmed/24831554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12319
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