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Serum amyloid A induces interleukin-6 in dermal fibroblasts via Toll-like receptor 2, interleukin-1 receptor-associated kinase 4 and nuclear factor-κB

Systemic sclerosis is an autoimmune idiopathic connective tissue disease, characterized by vasculopathy, inflammation and fibrosis. There appears to be a link between inflammation and fibrosis, although the exact nature of the relationship is unknown. Serum amyloid A (SAA) is an acute-phase protein...

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Detalhes bibliográficos
Main Authors: O'Reilly, Steven, Cant, Rachel, Ciechomska, Marzena, Finnigan, James, Oakley, Fiona, Hambleton, Sophie, van Laar, Jacob M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4212947/
https://ncbi.nlm.nih.gov/pubmed/24476318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12260
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