Engineering Acetyl Coenzyme A Supply: Functional Expression of a Bacterial Pyruvate Dehydrogenase Complex in the Cytosol of Saccharomyces cerevisiae

The energetic (ATP) cost of biochemical pathways critically determines the maximum yield of metabolites of vital or commercial relevance. Cytosolic acetyl coenzyme A (acetyl-CoA) is a key precursor for biosynthesis in eukaryotes and for many industrially relevant product pathways that have been intr...

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Bibliografski detalji
Glavni autori: Kozak, Barbara U., van Rossum, Harmen M., Luttik, Marijke A. H., Akeroyd, Michiel, Benjamin, Kirsten R., Wu, Liang, de Vries, Simon, Daran, Jean-Marc, Pronk, Jack T., van Maris, Antonius J. A.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Microbiology 2014
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4212835/
https://ncbi.nlm.nih.gov/pubmed/25336454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01696-14
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