Engineering Acetyl Coenzyme A Supply: Functional Expression of a Bacterial Pyruvate Dehydrogenase Complex in the Cytosol of Saccharomyces cerevisiae

The energetic (ATP) cost of biochemical pathways critically determines the maximum yield of metabolites of vital or commercial relevance. Cytosolic acetyl coenzyme A (acetyl-CoA) is a key precursor for biosynthesis in eukaryotes and for many industrially relevant product pathways that have been intr...

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Detalhes bibliográficos
Main Authors: Kozak, Barbara U., van Rossum, Harmen M., Luttik, Marijke A. H., Akeroyd, Michiel, Benjamin, Kirsten R., Wu, Liang, de Vries, Simon, Daran, Jean-Marc, Pronk, Jack T., van Maris, Antonius J. A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Microbiology 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4212835/
https://ncbi.nlm.nih.gov/pubmed/25336454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01696-14
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