Overproduction of Threonine Aldolase Circumvents the Biosynthetic Role of Pyruvate Decarboxylase in Glucose-Limited Chemostat Cultures of Saccharomyces cerevisiae

Pyruvate decarboxylase-negative (Pdc(−)) mutants of Saccharomyces cerevisiae require small amounts of ethanol or acetate to sustain aerobic, glucose-limited growth. This nutritional requirement has been proposed to originate from (i) a need for cytosolic acetyl coenzyme A (acetyl-CoA) for lipid and...

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Detalhes bibliográficos
Main Authors: van Maris, Antonius J. A., Luttik, Marijke A. H., Winkler, Aaron A., van Dijken, Johannes P., Pronk, Jack T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Physiology and Biotechnology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC154831/
https://ncbi.nlm.nih.gov/pubmed/12676688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.69.4.2094-2099.2003
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