Overproduction of Threonine Aldolase Circumvents the Biosynthetic Role of Pyruvate Decarboxylase in Glucose-Limited Chemostat Cultures of Saccharomyces cerevisiae

Pyruvate decarboxylase-negative (Pdc(−)) mutants of Saccharomyces cerevisiae require small amounts of ethanol or acetate to sustain aerobic, glucose-limited growth. This nutritional requirement has been proposed to originate from (i) a need for cytosolic acetyl coenzyme A (acetyl-CoA) for lipid and...

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Опубликовано в::	Appl Environ Microbiol
Главные авторы:	van Maris, Antonius J. A., Luttik, Marijke A. H., Winkler, Aaron A., van Dijken, Johannes P., Pronk, Jack T.
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Microbiology (ASM) 2003
Предметы:	Physiology and Biotechnology
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC154831/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12676688/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AEM.69.4.2094-2099.2003
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