Brain-Penetrating Nanoparticles Improve Paclitaxel Efficacy in Malignant Glioma Following Local Administration

[Image: see text] Poor drug distribution and short drug half-life within tumors strongly limit efficacy of chemotherapies in most cancers, including primary brain tumors. Local or targeted drug delivery via controlled-release polymers is a promising strategy to treat infiltrative brain tumors, which...

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Bibliografiske detaljer
Main Authors: Nance, Elizabeth, Zhang, Clark, Shih, Ting-Yu, Xu, Qingguo, Schuster, Benjamin S., Hanes, Justin
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2014
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4212792/
https://ncbi.nlm.nih.gov/pubmed/25259648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn504210g
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