Bromelain Surface Modification Increases the Diffusion of Silica Nanoparticles in the Tumor Extracellular Matrix

[Image: see text] Tumor extracellular matrix (ECM) represents a major obstacle to the diffusion of therapeutics and drug delivery systems in cancer parenchyma. This biological barrier limits the efficacy of promising therapeutic approaches including the delivery of siRNA or agents intended for therm...

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Detalhes bibliográficos
Main Authors: Parodi, Alessandro, Haddix, Seth G., Taghipour, Nima, Scaria, Shilpa, Taraballi, Francesca, Cevenini, Armando, Yazdi, Iman K., Corbo, Claudia, Palomba, Roberto, Khaled, Sm Z., Martinez, Jonathan O., Brown, Brandon S., Isenhart, Lucas, Tasciotti, Ennio
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4212787/
https://ncbi.nlm.nih.gov/pubmed/25119793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn502807n
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