One-pot synthesis of pH-responsive hybrid nanogel particles for the intracellular delivery of small interfering RNA

This report describes a novel, one-pot synthesis of hybrid nanoparticles formed by a nanostructured inorganic silica core and an organic pH-responsive hydrogel shell. This easy-to-perform, oil-in-water emulsion process synthesizes fluorescently-doped silica nanoparticles wrapped within a tunable coa...

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Veröffentlicht in:Biomaterials
Hauptverfasser: Khaled, Sm Z., Cevenini, Armando, Yazdi, Iman K., Parodi, Alessandro, Evangelopoulos, Michael, Corbo, Claudia, Scaria, Shilpa, Hu, Ye, Haddix, Seth G., Corradetti, Bruna, Salvatore, Francesco, Tasciotti, Ennio
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4785811/
https://ncbi.nlm.nih.gov/pubmed/26901429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2016.01.052
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