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CCL7 Is a Protective Factor Secreted by Mechanically Loaded Osteocytes

In a search for factors up-regulated by mechanical strain in osteocytes, we discovered that chemokine (C-C motif) ligand 7 (CCL7), a chemotactic myokine, was highly expressed in MLO-Y4 osteocyte-like cells. Although MLO-Y4 cells secrete potent chemotactic factors for osteoclast precursors, CCL7 was...

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Autori principali: Kitase, Y., Lee, S., Gluhak-Heinrich, J., Johnson, M.L., Harris, S.E., Bonewald, L.F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: SAGE Publications 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4212466/
https://ncbi.nlm.nih.gov/pubmed/25274752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0022034514553008
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