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An Improved Restriction Enzyme Accessibility Assay (REAA) for Analyzing Changes in Chromatin Structure in Samples of Limited Cell Number

Studies investigating mechanisms that control gene regulation frequently examine the accessibility of specific DNA sequences to nuclease cleavage. In general, sequences that are sensitive to nuclease cleavage are considered to be in an “open” chromatin conformation that is associated with regulatory...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ohkawa, Yasuyuki, Mallappa, Chandrashekara, Dacwag, Caroline S., Imbalzano, Anthony N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4212212/
https://ncbi.nlm.nih.gov/pubmed/22130859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-343-1_32
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