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Virulence and immunogenicity of a temperature-sensitive dengue-2 virus in lower primates.

Clones of dengue-2 virus were tested for virulence by inoculation of rhesus monkeys and chimpanzees. Although primates showed no overt signs of illness, inoculation with the parent virus or a subline of a large-plaque clone resulted in a viremia lasting 1 to 7 days. By these criteria, sublines of a...

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Detalhes bibliográficos
Main Authors: Harrison, V R, Eckels, K H, Sagartz, J W, Russell, P K
Formato: Artigo
Idioma:Inglês
Publicado em: 1977
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC421207/
https://ncbi.nlm.nih.gov/pubmed/409682
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