The Causal Effect of Vitamin D Binding Protein (DBP) Levels on Calcemic and Cardiometabolic Diseases: A Mendelian Randomization Study

BACKGROUND: Observational studies have shown that vitamin D binding protein (DBP) levels, a key determinant of 25-hydroxy-vitamin D (25OHD) levels, and 25OHD levels themselves both associate with risk of disease. If 25OHD levels have a causal influence on disease, and DBP lies in this causal pathway...

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Detalhes bibliográficos
Main Authors: Leong, Aaron, Rehman, Waheed, Dastani, Zari, Greenwood, Celia, Timpson, Nicholas, Langsetmo, Lisa, Berger, Claudie, Fu, Lei, Wong, Betty Y. L., Malik, Suneil, Malik, Rainer, Hanley, David A., Cole, David E. C., Goltzman, David, Richards, J. Brent
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4211663/
https://ncbi.nlm.nih.gov/pubmed/25350643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1001751
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