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Disrupting the Balance between Tumor Epithelia and Stroma is a Possible Therapeutic Approach for Pancreatic Cancer

Pancreatic ductal adenocarcinoma (PDAC) is a type of highly lethal malignant tumor. PDAC is locally invasive and is surrounded by a dense desmoplasia or fibrosis, which can involve adjacent vital structures. Previously, the effect of pancreatic stellate cells (PSCs) of stroma in the progression of P...

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Autori principali: Wang, Zheng, Li, Jiahui, Chen, Xin, Duan, Wanxing, Ma, Qingyong, Li, Xuqi
Natura: Artigo
Lingua:Inglês
Pubblicazione: International Scientific Literature, Inc. 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4211416/
https://ncbi.nlm.nih.gov/pubmed/25327552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.892523
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