Systematic Analysis of Time-Series Gene Expression Data on Tumor Cell-Selective Apoptotic Responses to HDAC Inhibitors

SAHA (suberoylanilide hydroxamic acid or vorinostat) is the first nonselective histone deacetylase (HDAC) inhibitor approved by the US Food and Drug Administration (FDA). SAHA affects histone acetylation in chromatin and a variety of nonhistone substrates, thus influencing many cellular processes. I...

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Main Authors: Qi, Yun-feng, Huang, Yan-xin, Dong, Yan, Zheng, Li-hua, Bao, Yong-li, Sun, Lu-guo, Wu, Yin, Yu, Chun-lei, Jiang, Hong-yu, Li, Yu-xin
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4211306/
https://ncbi.nlm.nih.gov/pubmed/25371703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/867289
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