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CLUH regulates mitochondrial biogenesis by binding mRNAs of nuclear-encoded mitochondrial proteins

Mitochondrial function requires coordination of two genomes for protein biogenesis, efficient quality control mechanisms, and appropriate distribution of the organelles within the cell. How these mechanisms are integrated is currently not understood. Loss of the Clu1/CluA homologue (CLUH) gene led t...

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Bibliographic Details
Main Authors: Gao, Jie, Schatton, Désirée, Martinelli, Paola, Hansen, Henriette, Pla-Martin, David, Barth, Esther, Becker, Christian, Altmueller, Janine, Frommolt, Peter, Sardiello, Marco, Rugarli, Elena I.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210445/
https://ncbi.nlm.nih.gov/pubmed/25349259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201403129
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