CLUH regulates mitochondrial biogenesis by binding mRNAs of nuclear-encoded mitochondrial proteins

Mitochondrial function requires coordination of two genomes for protein biogenesis, efficient quality control mechanisms, and appropriate distribution of the organelles within the cell. How these mechanisms are integrated is currently not understood. Loss of the Clu1/CluA homologue (CLUH) gene led t...

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Hlavní autoři: Gao, Jie, Schatton, Désirée, Martinelli, Paola, Hansen, Henriette, Pla-Martin, David, Barth, Esther, Becker, Christian, Altmueller, Janine, Frommolt, Peter, Sardiello, Marco, Rugarli, Elena I.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2014
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Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210445/
https://ncbi.nlm.nih.gov/pubmed/25349259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201403129
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