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Host cell entry of Middle East respiratory syndrome coronavirus after two-step, furin-mediated activation of the spike protein

Middle East respiratory syndrome coronavirus (MERS-CoV) is a newly identified betacoronavirus causing high morbidity and mortality in humans. The coronavirus spike (S) protein is the main determinant of viral entry, and although it was previously shown that MERS-CoV S can be activated by various pro...

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Detalhes bibliográficos
Main Authors: Millet, Jean Kaoru, Whittaker, Gary R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210292/
https://ncbi.nlm.nih.gov/pubmed/25288733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1407087111
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