Exome sequencing identifies FANCM as a susceptibility gene for triple-negative breast cancer

Inherited predisposition to breast cancer is known to be caused by loss-of-function mutations in BRCA1, BRCA2, PALB2, CHEK2, and other genes involved in DNA repair. However, most families severely affected by breast cancer do not harbor mutations in any of these genes. In Finland, founder mutations...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Kiiski, Johanna I., Pelttari, Liisa M., Khan, Sofia, Freysteinsdottir, Edda S., Reynisdottir, Inga, Hart, Steven N., Shimelis, Hermela, Vilske, Sara, Kallioniemi, Anne, Schleutker, Johanna, Leminen, Arto, Bützow, Ralf, Blomqvist, Carl, Barkardottir, Rosa B., Couch, Fergus J., Aittomäki, Kristiina, Nevanlinna, Heli
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210278/
https://ncbi.nlm.nih.gov/pubmed/25288723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1407909111
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados