Exome sequencing identifies FANCM as a susceptibility gene for triple-negative breast cancer

Inherited predisposition to breast cancer is known to be caused by loss-of-function mutations in BRCA1, BRCA2, PALB2, CHEK2, and other genes involved in DNA repair. However, most families severely affected by breast cancer do not harbor mutations in any of these genes. In Finland, founder mutations...

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Main Authors: Kiiski, Johanna I., Pelttari, Liisa M., Khan, Sofia, Freysteinsdottir, Edda S., Reynisdottir, Inga, Hart, Steven N., Shimelis, Hermela, Vilske, Sara, Kallioniemi, Anne, Schleutker, Johanna, Leminen, Arto, Bützow, Ralf, Blomqvist, Carl, Barkardottir, Rosa B., Couch, Fergus J., Aittomäki, Kristiina, Nevanlinna, Heli
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2014
主題:
Biological Sciences
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210278/
https://ncbi.nlm.nih.gov/pubmed/25288723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1407909111
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