Exome sequencing identifies FANCM as a susceptibility gene for triple-negative breast cancer

Inherited predisposition to breast cancer is known to be caused by loss-of-function mutations in BRCA1, BRCA2, PALB2, CHEK2, and other genes involved in DNA repair. However, most families severely affected by breast cancer do not harbor mutations in any of these genes. In Finland, founder mutations...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Kiiski, Johanna I., Pelttari, Liisa M., Khan, Sofia, Freysteinsdottir, Edda S., Reynisdottir, Inga, Hart, Steven N., Shimelis, Hermela, Vilske, Sara, Kallioniemi, Anne, Schleutker, Johanna, Leminen, Arto, Bützow, Ralf, Blomqvist, Carl, Barkardottir, Rosa B., Couch, Fergus J., Aittomäki, Kristiina, Nevanlinna, Heli
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2014
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210278/
https://ncbi.nlm.nih.gov/pubmed/25288723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1407909111
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires