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Cooperative Conformational Transitions Keep RecA Filament Active During ATPase Cycle

[Image: see text] The active, stretched conformation of the RecA filament bound to single-stranded DNA is required for homologous recombination. During this process, the RecA filament mediates the homology search and base pair exchange with a complementary sequence. Subsequently, the RecA filament d...

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Main Authors: Kim, Sung Hyun, Ragunathan, Kaushik, Park, Jeehae, Joo, Chirlmin, Kim, Doseok, Ha, Taekjip
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Chemical Society 2014
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210115/
https://ncbi.nlm.nih.gov/pubmed/25252114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja506363y
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