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The cohesin acetyltransferase Eco1 coordinates rDNA replication and transcription

Eco1 is the acetyltransferase that establishes sister-chromatid cohesion during DNA replication. A budding yeast strain with an eco1 mutation that genocopies Roberts syndrome has reduced ribosomal DNA (rDNA) transcription and a transcriptional signature of starvation. We show that deleting FOB1—a ge...

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Autors principals: Lu, Shuai, Lee, Kenneth K, Harris, Bethany, Xiong, Bo, Bose, Tania, Saraf, Anita, Hattem, Gaye, Florens, Laurence, Seidel, Chris, Gerton, Jennifer L
Format: Artigo
Idioma:Inglês
Publicat: BlackWell Publishing Ltd 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210108/
https://ncbi.nlm.nih.gov/pubmed/24631914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embr.201337974
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