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Transformation of quiescent adult oligodendrocyte precursor cells into malignant glioma through a multistep reactivation process
How malignant gliomas arise in a mature brain remains a mystery, hindering the development of preventive and therapeutic interventions. We previously showed that oligodendrocyte precursor cells (OPCs) can be transformed into glioma when mutations are introduced perinatally. However, adult OPCs rarel...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4210043/ https://ncbi.nlm.nih.gov/pubmed/25246577 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1414389111 |
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