Chromatin reader L(3)mbt requires the Myb–MuvB/DREAM transcriptional regulatory complex for chromosomal recruitment

Lethal malignant brain tumors (lmbt) result from the loss of the conserved transcriptional repressor l(3)mbt, in Drosophila melanogaster. Similar mutations in the human homolog L3MBTL1 correlate with some cancers. The protein’s C-terminal MBT repeats bind mono and dimethylated histones in vitro, whi...

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Detaylı Bibliyografya
Asıl Yazarlar: Blanchard, Daniel P., Georlette, Daphne, Antoszewski, Lisa, Botchan, Michael R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2014
Konular:
PNAS Plus
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210012/
https://ncbi.nlm.nih.gov/pubmed/25249635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1416321111
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