Chromatin reader L(3)mbt requires the Myb–MuvB/DREAM transcriptional regulatory complex for chromosomal recruitment

Lethal malignant brain tumors (lmbt) result from the loss of the conserved transcriptional repressor l(3)mbt, in Drosophila melanogaster. Similar mutations in the human homolog L3MBTL1 correlate with some cancers. The protein’s C-terminal MBT repeats bind mono and dimethylated histones in vitro, whi...

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Bibliografske podrobnosti
Main Authors: Blanchard, Daniel P., Georlette, Daphne, Antoszewski, Lisa, Botchan, Michael R.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2014
Teme:
PNAS Plus
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210012/
https://ncbi.nlm.nih.gov/pubmed/25249635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1416321111
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