Epigenetic dysregulation by nickel through repressive chromatin domain disruption

Investigations into the genomic landscape of histone modifications in heterochromatic regions have revealed histone H3 lysine 9 dimethylation (H3K9me2) to be important for differentiation and maintaining cell identity. H3K9me2 is associated with gene silencing and is organized into large repressive...

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Autors principals: Jose, Cynthia C., Xu, Beisi, Jagannathan, Lakshmanan, Trac, Candi, Mallela, Ramya K., Hattori, Takamitsu, Lai, Darson, Koide, Shohei, Schones, Dustin E., Cuddapah, Suresh
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2014
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210008/
https://ncbi.nlm.nih.gov/pubmed/25246589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1406923111
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