The behavioural response of mice lacking NK(1) receptors to guanfacine resembles its clinical profile in treatment of ADHD

BACKGROUND AND PURPOSE: Mice with functional ablation of substance P-preferring neurokinin-1 receptors (NK1R−/− mice) display behavioural abnormalities resembling those in attention deficit hyperactivity disorder (ADHD). Here, we investigated whether the ADHD treatment, guanfacine, alleviated the hy...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Pillidge, Katharine, Porter, Ashley J, Dudley, Julia A, Tsai, Yuan-Chen, Heal, David J, Stanford, S Clare
Formato: Artigo
Lenguaje:Inglês
Publicado: BlackWell Publishing Ltd 2014
Materias:
Themed Section: Animal Models in Psychiatry Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4209942/
https://ncbi.nlm.nih.gov/pubmed/25074741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12860
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares