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Cardiomyocyte-specific deficiency of ketone body metabolism promotes accelerated pathological remodeling

OBJECTIVE: Exploitation of protective metabolic pathways within injured myocardium still remains an unclarified therapeutic target in heart disease. Moreover, while the roles of altered fatty acid and glucose metabolism in the failing heart have been explored, the influence of highly dynamic and nut...

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Bibliografiske detaljer
Main Authors: Schugar, Rebecca C., Moll, Ashley R., André d’Avignon, D., Weinheimer, Carla J., Kovacs, Attila, Crawford, Peter A.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4209361/
https://ncbi.nlm.nih.gov/pubmed/25353003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2014.07.010
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