Cardiomyocyte-specific deficiency of ketone body metabolism promotes accelerated pathological remodeling

OBJECTIVE: Exploitation of protective metabolic pathways within injured myocardium still remains an unclarified therapeutic target in heart disease. Moreover, while the roles of altered fatty acid and glucose metabolism in the failing heart have been explored, the influence of highly dynamic and nut...

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Bibliographic Details
Main Authors: Schugar, Rebecca C., Moll, Ashley R., André d’Avignon, D., Weinheimer, Carla J., Kovacs, Attila, Crawford, Peter A.
Format: Artigo
Language:Inglês
Published: Elsevier 2014
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4209361/
https://ncbi.nlm.nih.gov/pubmed/25353003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2014.07.010
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