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Contrasting roles for histone 3 lysine 27 demethylases in acute lymphoblastic leukemia
T cell acute lymphoblastic leukemia (T-ALL) is a hematological malignancy with dismal overall prognosis, exhibiting up to a 25% relapse rate, mainly due to the absence of non-cytotoxic targeted therapy options. Despite the fact that drugs targeting the function of key epigenetic factors have been ap...
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Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4209203/ https://ncbi.nlm.nih.gov/pubmed/25132549 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13605 |
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