Diabetes Recovery By Age-Dependent Conversion of Pancreatic δ-Cells Into Insulin Producers

Total or near-total loss of insulin-producing β-cells is a situation found in diabetes (Type 1, T1D) (1,2). Restoration of insulin production in T1D is thus a major medical challenge. We previously observed in mice in which β-cells are completely ablated that the pancreas reconstitutes new insulin-p...

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Auteurs principaux: Chera, Simona, Baronnier, Delphine, Ghila, Luiza, Cigliola, Valentina, Jensen, Jan N., Gu, Guoqiang, Furuyama, Kenichiro, Thorel, Fabrizio, Gribble, Fiona M., Reimann, Frank, Herrera, Pedro L.
Format: Artigo
Langue:Inglês
Publié: 2014
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4209186/
https://ncbi.nlm.nih.gov/pubmed/25141178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13633
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