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Embryo-transfer of the F2 Postnatal Calorie Restricted Female Rat Offspring into a Control Intra-uterine Environment Normalizes the Metabolic Phenotype
OBJECTIVE: Postnatal calorie and growth restriction (PNGR) in the first generation (F1) rat female offspring causes a lean and glucose tolerant phenotype associated with hypoinsulinemia and reduced glucose-stimulated insulin secretion (GSIS). Despite the absence of gestational hyperglycemia in the F...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4208919/ https://ncbi.nlm.nih.gov/pubmed/23021963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.metabol.2012.08.026 |
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