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Pre- and Postnatal Calorie Restriction Perturbs Early Hypothalamic Neuropeptide and Energy Balance
Energy balance is regulated by circulating leptin concentrations and hypothalamic leptin receptor (ObRb) signaling via STAT3 but inhibited by SOCS3 & PTP1B. Leptin signaling enhances anorexigenic neuropeptides and receptor (POMC, MC3-R, MC4-R) activation while suppressing orexigenic neuropeptide...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4208917/ https://ncbi.nlm.nih.gov/pubmed/22388752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.23013 |
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