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Computational Design of Protein-Based Inhibitors of Plasmodium vivax Subtilisin-Like 1 Protease

BACKGROUND: Malaria remains a major global health concern. The development of novel therapeutic strategies is critical to overcome the selection of multiresistant parasites. The subtilisin-like protease (SUB1) involved in the egress of daughter Plasmodium parasites from infected erythrocytes and in...

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Bibliographic Details
Main Authors: Bastianelli, Giacomo, Bouillon, Anthony, Nguyen, Christophe, Le-Nguyen, Dung, Nilges, Michael, Barale, Jean-Christophe
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4208747/
https://ncbi.nlm.nih.gov/pubmed/25343504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109269
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