Rhabdomyosarcoma: Current Challenges and Their Implications for Developing Therapies

Rhabdomyosarcoma (RMS) represents a rare, heterogeneous group of mesodermal malignancies with skeletal muscle differentiation. One major subgroup of RMS tumors (so-called “fusion-positive” tumors) carries exclusive chromosomal translocations that join the DNA-binding domain of the PAX3 or PAX7 gene...

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Bibliografiske detaljer
Main Authors: Hettmer, Simone, Li, Zhizhong, Billin, Andrew N., Barr, Frederic G., Cornelison, D.D.W., Ehrlich, Alan R., Guttridge, Denis C., Hayes-Jordan, Andrea, Helman, Lee J., Houghton, Peter J., Khan, Javed, Langenau, David M., Linardic, Corinne M., Pal, Ranadip, Partridge, Terence A., Pavlath, Grace K., Rota, Rossella, Schäfer, Beat W., Shipley, Janet, Stillman, Bruce, Wexler, Leonard H., Wagers, Amy J., Keller, Charles
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2014
Fag:
Banbury White Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4208704/
https://ncbi.nlm.nih.gov/pubmed/25368019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a025650
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