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Rhabdomyosarcoma: Current Challenges and Their Implications for Developing Therapies

Rhabdomyosarcoma (RMS) represents a rare, heterogeneous group of mesodermal malignancies with skeletal muscle differentiation. One major subgroup of RMS tumors (so-called “fusion-positive” tumors) carries exclusive chromosomal translocations that join the DNA-binding domain of the PAX3 or PAX7 gene...

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Autori principali: Hettmer, Simone, Li, Zhizhong, Billin, Andrew N., Barr, Frederic G., Cornelison, D.D.W., Ehrlich, Alan R., Guttridge, Denis C., Hayes-Jordan, Andrea, Helman, Lee J., Houghton, Peter J., Khan, Javed, Langenau, David M., Linardic, Corinne M., Pal, Ranadip, Partridge, Terence A., Pavlath, Grace K., Rota, Rossella, Schäfer, Beat W., Shipley, Janet, Stillman, Bruce, Wexler, Leonard H., Wagers, Amy J., Keller, Charles
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4208704/
https://ncbi.nlm.nih.gov/pubmed/25368019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a025650
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