Rhabdomyosarcoma: Current Challenges and Their Implications for Developing Therapies

Rhabdomyosarcoma (RMS) represents a rare, heterogeneous group of mesodermal malignancies with skeletal muscle differentiation. One major subgroup of RMS tumors (so-called “fusion-positive” tumors) carries exclusive chromosomal translocations that join the DNA-binding domain of the PAX3 or PAX7 gene...

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Detalles Bibliográficos
Main Authors: Hettmer, Simone, Li, Zhizhong, Billin, Andrew N., Barr, Frederic G., Cornelison, D.D.W., Ehrlich, Alan R., Guttridge, Denis C., Hayes-Jordan, Andrea, Helman, Lee J., Houghton, Peter J., Khan, Javed, Langenau, David M., Linardic, Corinne M., Pal, Ranadip, Partridge, Terence A., Pavlath, Grace K., Rota, Rossella, Schäfer, Beat W., Shipley, Janet, Stillman, Bruce, Wexler, Leonard H., Wagers, Amy J., Keller, Charles
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2014
Assuntos:
Banbury White Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4208704/
https://ncbi.nlm.nih.gov/pubmed/25368019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a025650
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