Rhabdomyosarcoma: Current Challenges and Their Implications for Developing Therapies

Rhabdomyosarcoma (RMS) represents a rare, heterogeneous group of mesodermal malignancies with skeletal muscle differentiation. One major subgroup of RMS tumors (so-called “fusion-positive” tumors) carries exclusive chromosomal translocations that join the DNA-binding domain of the PAX3 or PAX7 gene...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Hettmer, Simone, Li, Zhizhong, Billin, Andrew N., Barr, Frederic G., Cornelison, D.D.W., Ehrlich, Alan R., Guttridge, Denis C., Hayes-Jordan, Andrea, Helman, Lee J., Houghton, Peter J., Khan, Javed, Langenau, David M., Linardic, Corinne M., Pal, Ranadip, Partridge, Terence A., Pavlath, Grace K., Rota, Rossella, Schäfer, Beat W., Shipley, Janet, Stillman, Bruce, Wexler, Leonard H., Wagers, Amy J., Keller, Charles
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2014
Sujets:
Banbury White Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4208704/
https://ncbi.nlm.nih.gov/pubmed/25368019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a025650
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