Rhabdomyosarcoma: Current Challenges and Their Implications for Developing Therapies

Rhabdomyosarcoma (RMS) represents a rare, heterogeneous group of mesodermal malignancies with skeletal muscle differentiation. One major subgroup of RMS tumors (so-called “fusion-positive” tumors) carries exclusive chromosomal translocations that join the DNA-binding domain of the PAX3 or PAX7 gene...

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Hlavní autoři: Hettmer, Simone, Li, Zhizhong, Billin, Andrew N., Barr, Frederic G., Cornelison, D.D.W., Ehrlich, Alan R., Guttridge, Denis C., Hayes-Jordan, Andrea, Helman, Lee J., Houghton, Peter J., Khan, Javed, Langenau, David M., Linardic, Corinne M., Pal, Ranadip, Partridge, Terence A., Pavlath, Grace K., Rota, Rossella, Schäfer, Beat W., Shipley, Janet, Stillman, Bruce, Wexler, Leonard H., Wagers, Amy J., Keller, Charles
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2014
Témata:
Banbury White Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4208704/
https://ncbi.nlm.nih.gov/pubmed/25368019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a025650
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