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c-Jun activation in Schwann cells protects against loss of sensory axons in inherited neuropathy

Charcot–Marie–Tooth disease type 1A is the most frequent inherited peripheral neuropathy. It is generally due to heterozygous inheritance of a partial chromosomal duplication resulting in over-expression of PMP22. A key feature of Charcot–Marie–Tooth disease type 1A is secondary death of axons. Prev...

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Detalhes bibliográficos
Main Authors: Hantke, Janina, Carty, Lucy, Wagstaff, Laura J., Turmaine, Mark, Wilton, Daniel K., Quintes, Susanne, Koltzenburg, Martin, Baas, Frank, Mirsky, Rhona, Jessen, Kristján R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4208468/
https://ncbi.nlm.nih.gov/pubmed/25216747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awu257
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