c-Jun in Schwann cells promotes axonal regeneration and motoneuron survival via paracrine signaling

The AP-1 transcription factor c-Jun is a master regulator of the axonal response in neurons. c-Jun also functions as a negative regulator of myelination in Schwann cells (SCs) and is strongly reactivated in SCs upon axonal injury. We demonstrate here that, after injury, the absence of c-Jun specific...

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Detalhes bibliográficos
Main Authors: Fontana, Xavier, Hristova, Mariya, Da Costa, Clive, Patodia, Smriti, Thei, Laura, Makwana, Milan, Spencer-Dene, Bradley, Latouche, Morwena, Mirsky, Rhona, Jessen, Kristjan R., Klein, Rüdiger, Raivich, Gennadij, Behrens, Axel
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392945/
https://ncbi.nlm.nih.gov/pubmed/22753894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201205025
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