Perturbations in small molecule synthesis uncovers an iron-responsive secondary metabolite network in Aspergillus fumigatus

Iron plays a critical role in survival and virulence of the opportunistic pathogen Aspergillus fumigatus. Two transcription factors, the GATA-factor SreA and the bZip-factor HapX oppositely monitor iron homeostasis with HapX activating iron acquisition pathways (e.g., siderophores) and shutting down...

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Detalhes bibliográficos
Main Authors: Wiemann, Philipp, Lechner, Beatrix E., Baccile, Joshua A., Velk, Thomas A., Yin, Wen-Bing, Bok, Jin Woo, Pakala, Suman, Losada, Liliana, Nierman, William C., Schroeder, Frank C., Haas, Hubertus, Keller, Nancy P.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4208449/
https://ncbi.nlm.nih.gov/pubmed/25386169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2014.00530
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