Immunomodulatory effects of 17-O-acetylacuminolide in RAW264.7 cells and HUVECs: involvement of MAPK and NF-κB pathways

The terpenoid 17-O-acetylacuminolide (AA) was shown to inhibit the production of several inflammatory mediators. However, the mechanisms by which this compound elicited its anti-inflammatory activity remain to be elucidated. In this study, we analyzed the effects of AA on inflammatory gene expressio...

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Detalhes bibliográficos
Main Authors: Achoui, Mouna, Heyninck, Karen, Looi, Chung Yeng, Mustafa, Ali Mohd, Haegeman, Guy, Mustafa, Mohd Rais
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2014
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4208353/
https://ncbi.nlm.nih.gov/pubmed/25349474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S68659
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