In Vitro and In Vivo Anti-Inflammatory Activity of 17-O-Acetylacuminolide through the Inhibition of Cytokines, NF-κB Translocation and IKKβ Activity

BACKGROUND AND PURPOSE: 17-O-acetylacuminolide (AA), a diterpenoid labdane, was isolated for the first time from the plant species Neouvaria foetida. The anti-inflammatory effects of this compound were studied both in vitro and in vivo. EXPERIMENTAL APPROACH: Plant extracts were initially tested aga...

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Detalhes bibliográficos
Main Authors: Achoui, Mouna, Appleton, David, Abdulla, Mahmood Ameen, Awang, Khalijah, Mohd, Mustafa Ali, Mustafa, Mohd Rais
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995738/
https://ncbi.nlm.nih.gov/pubmed/21152019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015105
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