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Gene–environment interaction involved in cholangiocarcinoma in the Thai population: polymorphisms of DNA repair genes, smoking and use of alcohol

OBJECTIVE: Cholangiocarcinoma (CCA) is the most common malignancy in a Northeast Thai population. Smoking and alcohol drinking are associated with the production of free radical intermediates, which can cause several types of DNA lesions. Reduced repair of these DNA lesions would constitute an impor...

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Autori principali: Songserm, Nopparat, Promthet, Supannee, Pientong, Chamsai, Ekalaksananan, Tipaya, Chopjitt, Peechanika, Wiangnon, Surapon
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Publishing Group 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4208049/
https://ncbi.nlm.nih.gov/pubmed/25335960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2014-005447
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