Gene–environment interaction involved in cholangiocarcinoma in the Thai population: polymorphisms of DNA repair genes, smoking and use of alcohol

OBJECTIVE: Cholangiocarcinoma (CCA) is the most common malignancy in a Northeast Thai population. Smoking and alcohol drinking are associated with the production of free radical intermediates, which can cause several types of DNA lesions. Reduced repair of these DNA lesions would constitute an impor...

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Detalhes bibliográficos
Main Authors: Songserm, Nopparat, Promthet, Supannee, Pientong, Chamsai, Ekalaksananan, Tipaya, Chopjitt, Peechanika, Wiangnon, Surapon
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2014
Assuntos:
Epidemiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4208049/
https://ncbi.nlm.nih.gov/pubmed/25335960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2014-005447
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