Whole-cell biotransformation systems for reduction of prochiral carbonyl compounds to chiral alcohol in Escherichia coli

Lactobacillus brevis alcohol dehydrogenase (Lb-ADH) catalyzes reduction of prochiral carbonyl compounds to chiral alcohol and meanwhile consumes its cofactor NADH into NAD(+), while the cofactor regeneration can be catalyzed by Candida boidinii formate dehydrogenase (Cb-FDH). This work presents thre...

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Detalhes bibliográficos
Main Authors: Li, Bingjuan, Li, Yuxia, Bai, Dongmei, Zhang, Xin, Yang, Huiying, Wang, Jie, Liu, Gang, Yue, Juejie, Ling, Yan, Zhou, Dongsheng, Chen, Huipeng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4208033/
https://ncbi.nlm.nih.gov/pubmed/25342633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep06750
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