Serine Racemase Regulated by Binding to Stargazin and PSD-95: POTENTIAL N-METHYL-d-ASPARTATE-α-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID (NMDA-AMPA) GLUTAMATE NEUROTRANSMISSION CROSS-TALK

d-Serine, an endogenous co-agonist for the glycine site of the synaptic NMDA glutamate receptor, regulates synaptic plasticity and is implicated in schizophrenia. Serine racemase (SR) is the enzyme that converts l-serine to d-serine. In this study, we demonstrate that SR interacts with the synaptic...

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Bibliografiska uppgifter
Huvudupphovsmän: Ma, Ting Martin, Paul, Bindu D., Fu, Chenglai, Hu, Shaohui, Zhu, Heng, Blackshaw, Seth, Wolosker, Herman, Snyder, Solomon H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2014
Ämnen:
Neurobiology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207978/
https://ncbi.nlm.nih.gov/pubmed/25164819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.571604
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