Manipulation of PBF/PTTG1IP Phosphorylation Status; a Potential New Therapeutic Strategy for Improving Radioiodine Uptake in Thyroid and Other Tumors

CONTEXT: The clinical effectiveness of ablative radioiodine treatment of thyroid tumors is limited by the availability of the sodium iodide symporter (NIS) at the plasma membrane (PM) for uptake of (131)I. A significant proportion of well-differentiated thyroid tumors are unable to concentrate suffi...

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Detalhes bibliográficos
Main Authors: Smith, V. E., Sharma, N., Watkins, R. J., Read, M. L., Ryan, G. A., Kwan, P. P., Martin, A., Watkinson, J. C., Boelaert, K., Franklyn, J. A., McCabe, C. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2013
Assuntos:
Endocrine Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207948/
https://ncbi.nlm.nih.gov/pubmed/23678037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2012-3640
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