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Physiological and pathological consequences of cellular senescence

Cellular senescence, a permanent state of cell cycle arrest accompanied by a complex phenotype, is an essential mechanism that limits tumorigenesis and tissue damage. In physiological conditions, senescent cells can be removed by the immune system, facilitating tumor suppression and wound healing. H...

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Autores principales: Burton, Dominick G. A., Krizhanovsky, Valery
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer Basel 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207941/
https://ncbi.nlm.nih.gov/pubmed/25080110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-014-1691-3
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