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Physiological and pathological consequences of cellular senescence

Cellular senescence, a permanent state of cell cycle arrest accompanied by a complex phenotype, is an essential mechanism that limits tumorigenesis and tissue damage. In physiological conditions, senescent cells can be removed by the immune system, facilitating tumor suppression and wound healing. H...

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Detalhes bibliográficos
Main Authors: Burton, Dominick G. A., Krizhanovsky, Valery
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Basel 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207941/
https://ncbi.nlm.nih.gov/pubmed/25080110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-014-1691-3
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