Notch1 regulates progenitor cell proliferation and differentiation during mouse yolk sac hematopoiesis

Loss-of-function studies have demonstrated the essential role of Notch in definitive embryonic mouse hematopoiesis. We report here the consequences of Notch gain-of-function in mouse embryo hematopoiesis, achieved by constitutive expression of Notch1 intracellular domain (N1ICD) in angiopoietin rece...

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Detalhes bibliográficos
Main Authors: Cortegano, I, Melgar-Rojas, P, Luna-Zurita, L, Siguero-Álvarez, M, Marcos, M AR, Gaspar, M L, de la Pompa, J L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207476/
https://ncbi.nlm.nih.gov/pubmed/24583642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.27
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