Overexpression of rod photoreceptor glutamic acid rich protein 2 (GARP2) increases gain and slows recovery in mouse retina

BACKGROUND: The rod photoreceptor cGMP-gated cation channel, consisting of three α- and one β subunit, controls ion flow into the rod outer segment (ROS). In addition to the β-subunit, the Cngb1 locus encodes an abundant soluble protein, GARP2 that binds stoichiometrically to rod photoreceptor cGMP...

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Main Authors: Sarfare, Shanta, McKeown, Alex S, Messinger, Jeffrey, Rubin, Glen, Wei, Hongjun, Kraft, Timothy W, Pittler, Steven J
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2014
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Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207353/
https://ncbi.nlm.nih.gov/pubmed/25323447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-014-0067-5
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