Dopaminergic Modulation of Cortical Plasticity in Alzheimer's Disease Patients

In animal models of Alzheimer's disease (AD), mechanisms of cortical plasticity such as long-term potentiation (LTP) and long-term depression (LTD) are impaired. In AD patients, LTP-like cortical plasticity is abolished, whereas LTD seems to be preserved. Dopaminergic transmission has been hypo...

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Detalhes bibliográficos
Main Authors: Koch, Giacomo, Di Lorenzo, Francesco, Bonnì, Sonia, Giacobbe, Viola, Bozzali, Marco, Caltagirone, Carlo, Martorana, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207345/
https://ncbi.nlm.nih.gov/pubmed/24859851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2014.119
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